In the early 1990s, Tisha pursued a career in music, releasing her debut album "Tisha" in 1991. The album spawned several hit singles, including "The Word Is Out" and "Tisha's Song." Her music style was a fusion of R&B, pop, and dance, showcasing her impressive vocal range and versatility.

Tisha has been married to actor Martin Lawrence since 1996, and they have two daughters together. The couple has been open about their relationship struggles and has spoken publicly about their experiences with marriage counseling.

Tisha's film career took off in the mid-1990s, with notable roles in movies like "Boomerang" (1992), "House Party 2" (1991), and "Steel Magnolias" (1990). Her performances earned her multiple award nominations, including a NAACP Image Award for Outstanding Supporting Actress in a Motion Picture.